2013 what predictions? Eh Sherpa

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Ok. I just put this here because I like Andrew Dice Clay. Here's my take. Let's look at what happened in 2012 and my predictions.
Here's what I said

1. In regards to DTC Genetics, the FDA won't shut you down if you are google.But you will have to give your test away for free to build your database

If 99 dollars isn't giving it away, I have no clue what is

2. In regards to Pharmacogenomic testing, most doctors won't use the service despite studies showing utility that have existed for 2 years.

They still didn't in 2012.
3. In regards to GWAS predisposition testing, it is mostly useless. It doesn't scare or heal you.......most of the time

Nothing has changed science wise with this statement

So Now, after months off I have to come up with brilliance. Really?
Navigenics=Dead DecodeMe=Dead Pathway=Weight Loss genetics 23andMe=Giving tests away next to free

DTC Genomics is not the play here. 

For personalized medicine to succeed, the clinicians still need to learn and the students need to teach.

Prediction 1. A true 1000 USD genome will come out in 2013, late November, early December

Prediction 2. Someone will sue 23andMe for privacy violations

Prediction 3. A big set of PGx data will be released....and ignored.

Prediction 4. Hillary Clinton will have either cancer or a stroke. Her health reports are suspect at best.

Prediction 5. Nutrigenomics will begin to have much more press coverage.

The Sherpa Says: I am here, blocking and tackling. Awaiting the next phase of the climb. 

Dealing with other people's pregnancies

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This is something I've been asked about a few times, and something I was just thinking about, so thought I'd share. In the months after Joshua's death, some people were hesitant to tell us they were pregnant in case they upset us, some tell us before anyone else because they want to tell us in person rather than on the grapevine. That really didn't bother me, I'm generally excited to hear about friends pregnancies. Ultrasounds were hard to look at, and baby showers were hard to go to, and still are. Joshua died 2 days after our baby shower, so baby showers just don't have that same level of fun anymore, memories of our loss just come flooding back.

The other thing that's hard to deal with is other people's loss, but for a slightly different reason - my heart just aches for them. A very close friend had an early miscarriage a few months ago, and my heart ached for her. Another good friend who has also had a rough year has just suffered a 2nd trimester loss, and it breaks my heart. I don't want anyone to ever feel the weight of loss like we did. I know a loss earlier in the pregnancy is probably a bit easier to deal with, but it's never easy, and once you start planning names, planning how the room will look, what you'll need, changes you'll need to make, and start thinking about the future they're going to have, it's so hard to have it all ripped away.

It's something that really affects you for a long time, and I think it's important for people to understand that.

Catching up (yes I'm still alive)

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It's been a really busy few months! I'll go back to September.

We went on holiday to the Seychelles and Dubai for 2 weeks in September which was fabulous. My aunt Vicki lives there with her husband Chris and their two boys, Jack and Harry. Chris has a job as part of the United Nations, which is based in the Seychelles and they've been living there about 4 years now.

The Seychelles was fascinating. The economy is completely broken - they have the highest level of debt of any other country, and since we were there the International Monetary Fund has agreed on a $26 million rescue package, and the currency has floated and been devalued. A lot of things were run down, the roads were terrible, there's a big divide between the rich and poor and everything has to be imported, so the black market is rife.

But the beaches were gorgeous, the weather was fabulous, the sky was oh so clear at night, and the stars were stunning. Sitting out on Vicki and Chris' deck every evening watching the night sky was an amazing way to relax. We were a very short walk from the beach, and just enjoyed our 10 days there relaxing.

It was great to spend quality time with Vicki, Chris and the boys. Vicki lived with us for a few years when I was younger, so I've always felt very close to her, and Jack and Harry are such great kids, we had a lot of fun with them.

Here's a few pics from the trip:

The markets



Amazingly clear water



Full moon over the fishing boats that were at port due to the worries over the Somalian pirates



We hiked to a beach called Anse Major, which was quiet, and so pretty



On our way to Anse Major




View from Vicki and Chris' balcony



Everyone. Vicki doesn't usually look so grim, and no, Andrew didn't bother with shaving while away :)



A couple of gorgeous sunrises







After Seychelles we spent a few days in Dubai on the way home since we were flying with Emirates (best airline I've ever flown with by a long shot), and stopping in Dubai anyway.

It was Ramadan, so we couldn't eat or drink in public during daylight hours, and a number of places were either closed for the month, or closed for a few hours in the afternoon, but it wasn't a big deal. We had a really nice hotel which we got a great deal on due it being Ramadan, and therefore the low season, the city in general wasn't too busy, and we just did a double decker open top tour bus tour the 2 days we were there, which supplied us with complimentary cold bottles of water which we guzzled as soon as we got on the bus - so we probably drank more water than we would have otherwise.

It was stinking hot - over 40 c, and about 90% humidity, and the heat was disgustingly oppressive. We had a fabulous time though. It was such an interesting place, and there was so much to see and do. And being so hot, it made us very aware that we were in a desert, and the regular calls to prayer from the temples made the whole experience more authentic. It's a place I would like to go back to some time to further explore - 2 and a bit days definitely wasn't enough!

Some pics:

Down on the water - there were boats coming and going loading up with goods to be transported to other nearby countries, carrying tourists around, and general water taxis for transport.




A small selection of gold in one of the windows at the Gold Souk (market)



A shopping centre called Wafi - it had designer shops, and an upmarket "traditional" souk area - the place was deserted due to Ramadan, and most of the shops weren't opening the entire month.



One of the water taxis



Dubai is a construction zone! There were cranes everywhere you looked. The sky was never clear, it's pretty much one big sand storm. And this highway made American highways look tame!



The new Metro system they are building which will make a huge difference to traffic - you can see Burj Dubai in the background which will be the world's tallest building



In front of Burj Al Arab, Jumeirah - the water there was toasty warm!



And then Ski Dubai... so bizarre!



One of the big mosques



One of the mosques near us. They were having the evening iftar buffet (breaking of the daily fast)



And Andrew on Dubai Creek at sunset



The rest of the photos are here

I'm a Golden Retriever!

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According to this website, if I was a dog breed, I'd be a Golden Retriever :)



Yep, sounds like me :)

Golden Retriever

The Charmer

Laid-back, sociable and well-groomed, you've got your own hip little pack of groupies who just love to be around you. You have a brain inside that adorable little head of yours, though you use it mostly to organize your hectic social calendar. You never poop out at parties, and since you're popular with ladies and men, as well as children and adults, you dish out your wit, charm and luck to whomever is close enough to bask in it. The top dog likes you and wants to be your best friend, despite the fact that he doesn't really know what the heck you do. No one does, in fact, but everyone loves you all the same. A true foodie, you’ve got your keen ears fine-tuned to make sure you don't miss out on the opening of a trendy new place to nosh. But your youthful days of being able to wolf down food 24-7 are wagging behind you, meaning you've got to watch what you eat so you don’t pull a Brando and outgrow your coats.

The kitties and their Valentine's Day dates!

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The girls had a lovely time for Valentine's Day. They all had very handsome dates, and they dined on caviar, drank the worlds finest milk, and indulged in some catnip to top off the evening ;)

This is Lily, my middle girl, and her date Stoli, a handsome Russian Blue





Smudge, and her date, Luxor who is an Egyptian Mau.





Stoli and Luxor are brothers and best friends, and Smudge and Lily are sisters and best friends, so they double dated :-) Their mum, Renovia, does amazing art work, particularly cat sculptures, so check out her Etsy store if you're looking for a good present.

And last, but not least - Stumpy and her date, Dorian Grey aka Dorky. They make a good pair!

More revolving door antics with Obamacare

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I have commented before about the happy feet of Elizabeth Fowler and her travels in and out of government and in and out of the industries materially affected by the branch of government in which she "served".See here for earlier commentary.

Now a similar tale can be told in regard to a major player in the governmental regulation of the health  insurance industry.Steve Larsen's resume is similar to Dr. Fowler. As outlined here he worked with an insurance company and then played a key role in HHS  dealing with insurance regulation as regards ACA and now back to insurance, this with a subsidiary of a company who was the beneficiary of a large HHS contract while Larsen was employed by HHS.

Larsen left his position as head of HHS's Center for Consumer Information and Insurance Oversight shortly before SOCTUS ruled Obamacare was constitutional and is now an executive VP with the UHG subsidiary Optum. Mr. Larsen also played a role in one of favorite examples of the social justice brought about by Obamacare,the granting of exemptions to friends of the administration. See here.

The Tenth Commandment and Hayek were right about envy

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Quotes for the day From FA Hayek and PJ O'Rourke bring a year-end message about envy and social justice.

Quoting  the economist, Anthony de Jasay quoting Hayek.

"No effort to make society drabber will make in drab enough to relieve envy. Hayek,invoking Mill, pleads that if we value a free society, it is imperative 'that we not countenance envy, not sanction its demands by camouflaging it as social justice, but treat it.. as the most anti-social and evil of all passions' "

PJ O'Rourke, whose scholarly credentials include having actually read  Smith 's Wealth on Nations in the original English, has this to say about the envy and coveting things:

"The Tenth Commandment sends a message to all the jerks who want redistribution of wealth, higher taxes, more government programs, more government regulation, more government, less free enterprise, and less freedom. And the message is clear and concise: Go to hell."




References:

Page 198. The State, Anthony de Jasay
An Alternative Inaugural Speech" (18 January 2005) by PJ O'Rourke